Optimize Mental Health with Precision Medicine
Transforming limited data into comprehensive clinical insights for managing neurodivergent and psychiatric conditions[.
Neurodivergence and psychiatric conditions are among the most complex in medicine, involving medications with narrow therapeutic windows and major adherence challenges. AppMed™ empowers clinicians to optimize care with continuous monitoring in real-time:
- Ease the collection of validated psychiatric patient-reported outcomes (PRO) data.
- Track adherence with connected drug dispensing devices.
- Monitor therapeutic drug levels via at-home microsampling
Clinical Reality — Psychiatric Care
“The therapeutic window for many psychiatric medications is narrow, and patient-to-patient variability is extreme — yet most dosing decisions are made without a single objective plasma level measurement.”
— Adapted from CANMAT Clinical Guidelines, Psychopharmacology
50%
Psychiatric patients non-adherent within 6 months of initiation
-Syst Rev. 2020 Jan 16;9(1):17
5×
Non-adherent patients with schizophrenia have been found to have a 5-fold increase in relapse risk.
-Front Neurosci. 2020 Oct 9;14:531763
The Clinical Gap
Where Psychiatric
Care Falls Short
Mental Health treatment currently relies mostly on patient-reported data, yet the healthcare system sees patients only during brief, scheduled appointments.
01
The Pitfall of Recall Bias
When patients are asked to recall and report their symptoms only at appointments, it reflects a single moment rather than the entire preceding month. This recall bias systematically distorts the clinical picture, often resulting in suboptimal dosing and management decisions.
02
Late Detection of Relapse Signals
Early warning signs, uch as sleep disruption, irritability, and medication changes, ften emerge days or weeks before a psychiatric crisis. Without continuous monitoring, these signals go undetected and can result in hospitalization.
03
Lack of Accurate Adherence Data
Continuous tracking of medication adherence provides clear, actionable data on whether patients are taking their prescriptions as intended. Early identification of non-adherence enables timely intervention and helps prevent psychiatric relapse.
04
Narrow Therapeutic Windows
Psychiatric medications show significant patient-to-patient variability. Individualized dosing based on confirmed plasma levels enables evidence-based, optimized therapy with a maximum of efficiency while minimizing adverse effects.
What AppMed™ Offers
Three Streams That
Make Mental Health Care Objective
AppMed™ closes the most critical gaps in psychiatric care—not with generic wellness apps, but with clinical-grade, structured, objective clinical solutions fully integrated into point-of-care workflows.
Validated Psychiatric PROs
Continuous
Real-Time Symptom Assessment
Validated psychiatric questionnaires are automatically submitted to patients between appointments to capture real-time symptom trajectories that reflect daily life rather than just appointment-day snapshots.
- Condition-validated PRO tools
- Longitudinal clinical trends for clinical review
- Early warning signals for clinical deterioration Easy access to input from allied professionals
- Easy access to input from allied professionals and caregivers
Connected medication dispensing systems and patient-reported intake logs provide an objective, timestamped adherence record for psychiatric medications, the most critical and most unmeasured variable in mental health outcomes.
- Timestamped medication intake logs via connected MDS
- Automatic alerts for adherence gaps above clinical thresholds
- Adherence trend analysis for relapse prevention planning
Adherence Monitoring
Objective
Medication Tracking
Psychiatric TDM
At-Home Microsampling
for Drug Monitoring
Volumetric microsampling allows patients to collect dried blood spot samples at home, enabling therapeutic drug monitoring (TDM). This provides objective plasma level data without a clinic visit.
- Convenient blood analysis
- Pharmacokinetic variability assessment for dose individualization
- Results are integrated directly into the AppMed™ dashboard.
The Clinical Pathway
Three Proven Pathways
AppMed™ Elevates Care
AppMed™ supports superior management of key mental health conditions through patient-reported outcomes, narrow therapeutic window (NTW) medication monitoring, and adherence tracking. Currently, AppMed™ is implemented in three conditions, each with tailored monitoring tools and clinical alert settings.
Pathway 01
ADHD Pathway
AppMed™ consolidates real-time patient-recorded data into a comprehensive, easy-to-interpret clinical profile, supporting more informed decisions at every step of care.
Structured monitoring of ADHD treatment, including validated symptom tracking, adherence monitoring, Medication PK/PD Model Calculator and Therapeutic Drug Monitoring (TDM), enabling evidence-based titration and continuous treatment optimization.
- ADHD-RS, Conners, BRIEF validated scales
- Caregiver-reported observations (pediatric/adult)
- Functional outcome monitoring (school, work, QoL)
- Medication timing and dose adherence tracking
- Stimulant plasma level monitoring via microsampling
Pathway 02
Schizophrenia Pathway
Clinical-grade monitoring for schizophrenia, combining validated symptom assessment with objective adherence tracking and antipsychotic therapeutic drug monitoring through at-home microsampling.
- PANSS, BPRS symptom monitoring
- Early relapse warning signal detection
- Metabolic side effect tracking (weight, glucose)
- Adherence monitoring for LAI and oral antipsychotics
- Antipsychotic plasma levels (clozapine, risperidone, olanzapine)
Pathway 02
Depression & Deprescribing Protocol
AppMed™ consolidates real-time patient-recorded data into a comprehensive, easy-to-interpret clinical profile, supporting more informed decisions at every step of care.
Structured monitoring of depression treatment and deprescribing medication, including validated symptom tracking, adherence monitoring, and Therapeutic Drug Monitoring (TDM), enabling evidence-based titration and continuous treatment optimization.
- PHQ-9, GAD-7 validated scales
- Caregiver-reported observations
- Functional outcome monitoring
- Medication timing and dose adherence tracking
- Plasma level monitoring via microsampling
56%
Of patients with schizophrenia are non-adherent to antipsychotic medication, making it the leading preventable cause of relapse
— Semahegn et al., Systematic Reviews, 2020
5×
Non-adherent patients with schizophrenia have a 5-fold increase in relapse risk compared to those who remain on treatment
— Robinson et al. / Caseiro et al., cited in Frontiers in Psychiatry, 2020
1 in 2
Canadians will have a mental illness by age 40, yet only 1 in 3 who need mental health care report their needs are fully met
— CAMH Mental Health Statistics
The Clinical Gap
Objective Data for
Complex Psychiatric therapy
AppMed™ integrates the three data streams most absent from current psychiatric practice, replacing guesswork with structured, objective clinical evidence.
Coming soon
Psychiatric TDM — Supported Drug Classes
AppMed™ microsampling supports plasma monitoring for the key psychiatric drug classes with narrow therapeutic windows or high inter-patient variability.
Clozapine
200–600 ng/mL
Risperidone
20–60 ng/mL
Olanzapine
20–80 ng/mL
Methylphenidate
Variable
All samples collected at home via fingerprick microsampling kit, results returned to clinician dashboard within 5 business days
Consent is captured, the individualized treatment protocol is configured, and baseline patient-reported outcomes (PROs) are collected at the first visit.
PRO scores, medication logs, and functional assessments are delivered via the patient portal — ensuring consistent, structured daily data collection.
Patient self-collects a dried blood spot at home, mails it to a certified laboratory, and results are seamlessly integrated into the AppMed™ dashboard.
Clinical trajectories, adherence trends, and TDM results are unified in one dashboard. Automated alerts fire the moment thresholds are crossed — enabling proactive intervention.
Dose adjustments are guided by objective evidence — not guesswork. The patient is informed and the treatment protocol is updated accordingly.
Take the Next Step
See AppMed™ in Your
Mental Health Program
Request a clinical demonstration tailored to your Mental Health program. We’ll show you exactly how the data works for your patient population.
Mental health specialists · 24h response · Quebec-based clinical team